SKCCC Shared Resources | Cell Imaging
Recent Publications
Essential function of Chk1 can be uncoupled from DNA damage checkpoint and replication control.
Wilsker D, Petermann E, Helleday T, Bunz F.
Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20752-7. Epub 2008 Dec 17.

Deficiency of bloom syndrome helicase activity is radiomimetic.
Horowitz DP, Topaloglu O, Zhang Y, Bunz F.
Cancer Biol Ther. 2008 Nov 4;7(11). [Epub ahead of print]

PJ Hurley, D Wilsker and F Bunz.
Human cancer cells require ATR for cell cycle progression following exposure to ionizing radiation.
/Oncogene / 1-8, 2006
.

Nakakura EK, Sriuranpong V, Kunnimalaiyaan M, Hsiao E, , Schuebel KE, Chen H, Borges MW, Jin N, Collins BJ, Nelkin BD, Chen H, Ball DW.
Regulation of Neuroendocrine Differentiation in Gastrointestinal Carcinoid Tumor Cells by Notch Signaling. /Journal of Clinical Endocrinology and Metabolism
/ 90:4350-6, 2005

Strock CJ, Park JI, Rosen M, Ruggeri B, Denmeade SR, Ball DW, Nelkin BD.
Activity of Irinotecan and the tyrosine kinase inhibitor CEP-751 in medullary thyroid cancer.
/Journal of Clinical Endocrinology and Metabolism/ 91:79-84, 2006.

Strock CJ, Park JI, Nakakura EK, Bova GS, Isaacs JT, Ball DW and Nelkin BD
Cdk5 activity controls cell motility and metastatic potential of prostate cancer cell.
Cancer Res 66: 7509-15, 2006.

Eun-Joo Kim, Jong-In Park, and Barry D. Nelkin IFI16 Is an Essential Mediator of Growth Inhibition, but Not Differentiation, Induced by the Leukemia Inhibitory Factor/JAK/STAT Pathway in Medullary Thyroid Carcinoma Cells* J. Biol. Chem., Vol. 280, Issue 6, 4913-4920, February 11, 2005

Elias T. Zambidis, Bruno Peault, Tea Soon Park, Fred Bunz, and Curt I. Civin Hematopoietic differentiation of human embryonic stem cells progresses through sequential hematoendothelial, primitive, and definitive stages resembling human yolk sac development Blood. 2005 Aug 1;106(3):860-70. Epub 2005 Apr 14.

Susan Dalrymple1, Lizamma Antony1, Yi Xu1, Aarti R. Uzgare1, Julia T. Arnold1, Jurga Savaugeot2, Lori J. Sokoll1,2,3, Angelo M. De Marzo1,2,3 and John T. Isaacs1,2
Role of Notch-1 and E-Cadherin in the Differential Response to Calcium in Culturing Normal versus Malignant Prostate Cells Cancer Research 65, 9269-9279, October 15, 2005

Ivan V. Litvinov1,2, Donald J. Vander Griend3, Yi Xu1, Lizamma Antony1, Susan L. Dalrymple1 and John T. Isaacs1,2,3
Low-Calcium Serum-Free Defined Medium Selects for Growth of Normal Prostatic Epithelial Stem Cells Cancer Research 66, 8598-8607, September 1, 2006

Ball DW, Jin N, Rosen DM, Dackiw A, Sidransky D, Xing M, Nelkin BD.
Selective growth inhibition in BRAF mutant thyroid cancer: Effect of the MEK Inhibitor AZD6244
, in submission, 2007.

Our Goal

To provide state-of-the-art imaging technologies to Cancer Center Members

Established in 1999, the Cell Imaging Core Facility’s goal is to provide state-of-the-art cell imaging technologies to SKCCC investigators. Direct support from the NIH and the SKCCC keeps the cost of these services low. Recent growth has allowed us to expand our range of services.

iLab Service Scheduling

Internal (JHMI) Users

For internal users (those that have JHED credentials), please login/register here:

https://skcccjhmi.corefacilities.org

External Users

For external users (anyone outside of Johns Hopkins) they can login here:

https://service_center/show_external/3000/cell_imaging

In order to use this service as an external user, you'll need to register here:

https://my.ilabsolutions.com/account/signup/42?sc_id=3000

Highlighted Services

Stereoscopic Microscopy
The Nikon SMZ 1500 fluorescent stereoscopic zoom microscope is suitable for quickly assessing the pr   


   

Laser Capture Microdissection
The PALM Laser-Microbeam System (Zeiss) has proven to be a valuable asset to the Core users. With t